In vivo Imaging Brain injuries stroke (Greifswald)

Application of two-photon microscopy to Aging and Neural Repair studies in a stroke model of enhanced neurogenesis. One position post-doc position or two doctoral positions.

Highly motivated postdoctoral/doctoral fellows with proven experience on a particular area mentioned above. English skills and publications are mandatory for these positions. Readiness for temporary employment abroad is assumed and experience in animal experiments is desired.

Prof. Dr. Aurel Popa-Wagner
Aging and Neural Repair Laboratory
Clinic of Neurology
Ernst-Moritz-Arndt University Greifswald
Ellernholz str. 1-2
17489 Greifswald
Germany

Phone: +49-3834-86 68 53
Facsimile: +49-3834-86 68 43
 Email: wagnerap@uni-greifswald.de

Scientist with focus on GIS-based Modelling of Plant Growth (m/f) VE02 (Pfatten, Auer (BZ), Südtirol, Italien)

Laimburg Research Centre for Agriculture and Forestry is the leading agricultural research institute in South Tyrol (Italy). By conducting basic as well as applied research we strive to provide solutions to emerging agricultural problems and to develop sustainable strategies for the future.

For the realisation of the EFRE project “VEGEMONT - Mapping of site suitability for Vegetable cultivation in Mountain areas”, we would like to expand our team of young and motivated scientists by recruiting an experienced

Scientist with focus on GIS-based Modelling of Plant Growth (m/f) VE02

for a 4-year project collaboration contract starting on the 1st of January 2012.

Main tasks will include acquisition, management and statistical analysis of GIS-based and agronomic data in order to forecast the suitability of cultivation sites for several vegetable crops. The remuneration will be based on the salary of a technical expert (functional level VIII) of the Autonomous Province of Bolzano.

Required qualifications:
•       Applicants are required to have an academic degree (MSc, PhD) with good knowledge of mathematical modelling of plant growth, mainly depending on meteorological factors; experience in modelling growth of crop plants, and especially vegetables, would be an advantage.
•       We expect basic knowledge in the use of GIS-software; programming in C+ language would be an advantage.
•       Fluent in Italian and/or German, good communication skills in oral and written English.
•       Candidates should be highly motivated, able to work independently in a research group and possess sound problem solving skills.

Equal opportunities:
The position is open to both genders, Law n. 903, 9/12/1977, art. 1. The policy and practice of the Laimburg Research Centre require that all staff are offered equal opportunities within employment.

To apply, please send your Curriculum Vitae (please add the following phrase to your CV, otherwise your application will not be considered: I consent to the use of my personal data in accordance with the provisions of decree 196/2003) and a cover letter including a brief description of research interests, personal experiences and motivations via e-mail to: giovanni.peratoner@provinz.bz.it.
The deadline for the submission of the applications is October, 31th 2011.

For further information, please refer to our website www.laimburg.it or contact us by phone under the number: +39 0471 969661 (Giovanni Peratoner).

Data treatment
All data supplied by applicants will be used only for the purposes of determining their suitability for the position and will be held in accordance with the principles of the Personal Data Protection Code, Legislative Decree no. 196 of 30 June 2003. By sending the Cv and application, the candidate will consent and authorize the Research Centre Laimburg to the use of his/her personal data.

Scientist in Agronomy (m/f) VE01 (Pfatten, Auer (BZ), Südtirol, Italien)

Laimburg Research Centre for Agriculture and Forestry is the leading agricultural research institute in South Tyrol (Italy). By conducting basic as well as applied research we strive to provide rapid solutions to emerging agricultural problems and to develop sustainable strategies for the future.

For the realisation of the EFRE project “VEGEMONT - Mapping of site suitability for Vegetable cultivation in Mountain areas”, we would like to expand our team of young and motivated scientists by recruiting an experienced

Scientist in Agronomy (m/f) VE01

for a 4-year project collaboration contract starting on the 1st of January 2012.

Main tasks will include acquisition and processing of data from agronomic field trials/surveys and management of GIS-based pedoclimatic data. The remuneration will be based on the salary of a technical expert (functional level VII) of the Autonomous Province of Bolzano.

Required qualifications:
•       Applicants are required to have a professional or academic degree in Agricultural Sciences (BSc or MSc) or a related discipline and good knowledge of management of agronomic field trials and data, preferably concerning vegetable crops.
•       Experience in the use of GIS and programming in C+ language would be an advantage.
•       Fluent in Italian and/or German, good communication skills in oral and written English.
•       Candidates should be highly motivated, able to work independently in a research group and possess sound problem solving skills.

Equal opportunities:
The position is open to both genders, Law n. 903, 9/12/1977, art. 1. The policy and practice of the Laimburg Research Centre require that all staff are offered equal opportunities within employment.

To apply, please send your Curriculum Vitae (please add the following phrase to your CV, otherwise your application will not be considered: I consent to the use of my personal data in accordance with the provisions of decree 196/2003) and a cover letter including a brief description of research interests, personal experiences and motivations via e-mail to: giovanni.peratoner@provinz.bz.it.
The deadline for the submission of the applications is October, 31th 2011.

For further information, please refer to our website www.laimburg.it or contact us by phone under the number: +39 0471 969661 (Giovanni Peratoner).

Data treatment
All data supplied by applicants will be used only for the purposes of determining their suitability for the position and will be held in accordance with the principles of the Personal Data Protection Code, Legislative Decree no. 196 of 30 June 2003. By sending the Cv and application, the candidate will consent and authorize the Research Centre Laimburg to the use of his/her personal data.

Postdoc position in bioinformatics (TVL E-13) (Heidelberg)

Interested in computational cellular network analysis?

We are a smaller research team of one postdoc, 5 phd-students, varying undergraduates and the group leader. We are now able to offer another postdoctoral fellowship position (starting at Nov 1, 2011 until May 2013 and presumably longer).

We are analyzing and modeling metabolism, signaling and regulatory networks of cancer cells using gene expression data from microarrays, RNA sequencing, and image data from RNAi knockdown screens. We employ machine learning methods, statistics, own developments (e.g. shaping out tumor specific regulation) to identify specific drug targets for cancer therapy and in particular for neuroblastoma tumors.

If you are interested in systematically detecting functional patterns of such data in networks, if you have a good experience in the analysis of high throughput data from functional genomics, and if you hold a degree in bioinformatics, physics, computer science, mathematics, biology or related subjects, we are looking forward to your application.

Rainer König
r.koenig@dkfz.de
Bioquant, IPMB, Universität Heidelberg
Heidelberg

PhD/Postdoc Position: Computational Physics of Granular Matter (Erlangen, Germany)

The Institute for Multiscale Simulation of Particulate Systems at the
Friedrich-Alexander-University Erlangen-Nuremberg, Germany, invites
applications for an open postdoc or PhD position.

Subject of our research is the dynamics of granular matter, that is,
dissipative many-particle systems. We investigate these systems
numerically (mainly Molecular Dynamics and CFD) as well as
analytically (Statistical Physics, Continuum Mechanics). Our theo-
retical work is closely related to experimental research which is
partly also performed in our group.

Main research subject of the successful candidate is the numerical
simulation of complex many-particle and multi-phase systems,
statistical physics and continuum mechanics of dissipative systems,
including visualization of the results. The research is performed
in direct cooperation with experimentalists. Some teaching of under-
graduate classes (1-2 hours per week) may also belong to the duties.

Successful applicants must hold a PhD or M.Sc. (or equivalent) in
physics or a related field. We expect the applicant to be experi-
enced with the numerical simulation of physical systems, excellent
skills in C/C++, preferably under Unix/Linux.

The positions are available for a period of 2 years with the option
of a continuation, dependent on funding. The deadline for applications
is October, 14th 2011.

For further information, see: http://www.mss.cbi.uni-erlangen.de

Solid-state NMR and Dynamic Nuclear Polarisation on Paramagnetic Membrane Proteins

We are looking for an open-minded, enthusiastic, committed and diligent individual with a background in chemistry, biochemistry, physics or biophysics (German Diploma/MSc equivalent). Previous hands-on experience with NMR or EPR spectroscopy will be very helpful.

The successful candidate will work with “conventional” as well as DNP-supported MAS-NMR on membrane proteins. The work can be extended towards method development in the area of (pulsed) DNP and/or paramagnetic solid state NMR.  The project will be carried out in close collaborations with groups from the Institutes for Biochemistry and Theoretical and Physical Chemistry.

We offer a state-of-the-art research infrastructure including solid-state NMR (850 and 600 MHz) and DNP (258GHz/393MHz) spectrometers. An academic staff scientist provides user support.  The lab is part of the Frankfurt Centre for Biomolecular Magnetic Resonance (BMRZ), the research network SFB 807 “Transport across membranes “ and the Cluster of Excellence “Macromolecular Complexes”. It takes part in various European research and infrastructure initiatives. The lab is located at the new Riedberg Campus of the Goethe University, which is a recognised hotspot for membrane protein research and magnetic resonance spectroscopy.

Enquiries and applications shall be addressed to Clemens Glaubitz (glaubitz@em.uni.frankfurt.de). The deadline for applications is October 30th 2011.

Methoden:
NMR, EPR, DNP, solid-state NMR, MAS-NMR, membrane protein biochemistry

Anfangsdatum: 1. Dezember 2011

geschätzte Dauer: 3 Jahre

Bezahlung: E13 1/2

Veröffentlichungen:
see website or contact C. Glaubitz

Homepage: http://www.uni-frankfurt.de/fb/fb14/BiochemieH/BPC/AK_Glaubitz/index.html

PhD/Postdoc Position: Computational Dynamics of Granular Flows,Erlangen, Germany

The Institute for Multiscale Simulation of Particulate Systems at the
Friedrich-Alexander-University Erlangen-Nuremberg, Germany, invites
applications for an open postdoc or PhD position.

Granular materials reveal a variety of uncommon and sometimes
unexpected effects. Using particle based numerical methods, we
aim to the explanation of these effects and the quantitative
prediction of the dynamics of granular flows and suspensions.
Given the wide range of application of granular matter in industrial
processes, the understanding of its flow characteristics may be also
of importance for the optimization of manufacturing processes.

The main objectives include the investigation of:
- flow behavior of fine powders under consideration of material
 parameters and system geometry

- effects of particle agglomeration

- properties of particulate systems under consideration of the size
 distribution as well as plastic deformations of particles

Large-scale particulate systems shall be simulated using realistic
numerical models, in close collaboration with experimental work.

The successful candidate should hold a PhD or M.Sc. (or equivalent)
in physics, engineering or a related field with a strong background
in numerical simulations. Excellent skills in Linux, C/C++, and
preferably in parallel computing are expected, as well as a healthy
team spirit.

The position is available for a period of 2 years with the option
of a continuation, dependent on funding. The deadline for applications
is October, 14th 2011.

For further information, see: http://www.mss.cbi.uni-erlangen.de

Scientist/scientific programmer, in the area of terrestrial ecosystem modelling (Garmisch Partenkirchen)

Main tasks will include to develop and evaluate the process-based
dynamic vegetation model LPJ-GUESS, to analyse and visualize model
output, and to oversee the model code maintenance and version control.

The scientist/scientific programmer will be placed in the institute’s
newly established plant-atmosphere group and establish her/his tasks
jointly with the group leader. Access to state-of-the art
computational facilities is provided. Questions addressed in the group
include the effects of environmental changes and multiple stresses on
plant- and vegetation growth, and interactions with biogeochemical and
water cycles. The groups’ activities contribute also to the
development of fully coupled Earth System models. The work is done in
close collaboration with a number of groups in Germany and Europe,
especially with the core LPJ-GUESS team at Lund university. The
appointee must be willing to travel and have very good spoken and
written skills in communicating in the English language.

We offer a position in a multi-disciplinary, collaborative research
environment with excellent research infrastructure and support, well
connected to national and international programs. Salary and benefits
will be based on the Collective Agreement for the German Public
Service Sector. Appointment will be initially for a period of two
years, with the possibility of extension.

For further information, see: <http://imk-ifu.kit.edu/jobs.php>

Professional requirements: a proven track-record in scientific
programming and code development. Expertise in C++, and in maintaining
and working with parallel Linux clusters is an advantage. The work
suits a formally trained programmer (computational sciences) with
interest in the environmental sciences or a natural scientist (e.g.,
meteorology, environmental engineering, environmental physics,
geoecology) with advanced skills in programming. Candidates on M.Sc.
or Ph.D. level can be considered.

The Karlsruhe Institute of Technology (KIT) is the fusion of the
former University of Karlsruhe and the Forschungszentrum Karlsruhe.
This makes KIT a unique institution in Germany, combining the missions
of a university and that of a national research centre in the
Helmholtz-Association. With a staff of 8000 and an annual budget of
EUR 650 Mio., KIT ranks among the largest institutions of research and
higher learning worldwide.

Enquiries and applications with the usual documentation (curriculum
vitae, certificates, list of publications, short outline of own
research and/or career interests, and the contact information for two
professional referees) shall be addressed to

Prof. Almut Arneth; Atmospheric Environmental Research;
Institute of Meteorology and Climate Research; Karlsruhe Institute of
Technology (KIT/IMK-IFU); Kreuzeckbahnstr. 19; 82467
Garmisch-Partenkirchen, Germany. E-mail: almut.arneth@imk.fzk.de

Complete applications received by 31 October 2011 will receive full consideration.

KIT strives to achieve gender balance at all levels of employment. We
therefore particularly encourage female candidates to apply for this
position. With appropriate qualifications, applications from persons
with handicaps will be treated with preference.

Prof. Almut Arneth
almut.arneth@imk.fzk.de
KIT/IMK-IFU
Garmisch Partenkirchen

Ansprechpartner: Prof. Almut Arneth, almut.arneth@imk.fzk.de

Postdoctoral researcher in Climate Change Biology/Ecology Project B2.13 [Ref. #B49a] (Frankfurt am Main)

The Biodiversity and Climate Research Centre (BiK-F) is a interdisciplinary institute with the mission to carry out internationally outstanding research on the interactions of biodiversity and climate change on the organism level. It has been founded by the Senckenberg Gesellschaft für Naturforschung, the Goethe-University Frankfurt am Main, and other partners. The Centre is funded by the Federal State of Hesse through its Initiative for the Development of Scientific and Economic Excellence (LOEWE).
It provides a new, dynamic research environment that integrates a variety of disciplines from both natural and social sciences. The Project Area B “Biodiversity Dynamics and Climate” and C “Adaptation and Climate” invites applications for the position of a

Postdoctoral researcher in “Climate Change Biology/Ecology”
Project B2.13 [Ref. #B49a]

The successful candidate will join a highly motivated team of scientists and research support staff who are working at the Senckenberg Research Station Gelnhausen (close to Frankfurt) and in Frankfurt on a variety of topics in stream/floodplain ecology, conservation and evolutionary biology. She/he will work on two projects, dealing with different aspects of climate change impacts on biodiversity:
(1) An interdisciplinary project with hydrological (by Prof. P. Döll, University of Frankfurt) and freshwater ecological (Dr. S. Jähnig) aspects, where the successful candidate will develop ecological response functions to stream discharge changes for benthic invertebrates and fish. (2) An interdisciplinary project to model the impacts of climate change on genetic diversity of various plant and animal taxa. In addition, the successful candidate is expected to contribute to managing the projects and to advising graduate students.

Essentials:
We are looking for a highly motivated candidate holding a PhD degree in a relevant subject (freshwater biology, ecology, evolutionary biology or a related subject), with a strong track record of international publications, and a sound modelling background. Candidates should have extensive experience with data analyses using statistical methods, especially the use of species distribution models, GIS and
R (including script writing). Candidates should have also experience with project planning and management. We are seeking an individual with excellent verbal and written English communication skills that is willing to co-operate with other research groups at Senckenberg, the University of Frankfurt, and the Biodiversity and Climate Research Centre (BiK-F).

Conditions of employment
The position is full-time (100%). Salary and benefits are according to a public service position in Germany (Hesse) (TVH-E13). Senckenberg wishes to increase the share of women in areas where they are underrepresented, and strongly encourages women to apply. Senckenberg has an affirmative action policy for the disabled and especially encourages them to apply.

The contract shall start in Febuary 2012 with initial employment for up to 24 months. The duty stations will be Gelnhausen and Frankfurt am Main, Germany.

Please send your application by post or e-mail, including 1) a cover letter outlining relevant background and work experience, 2) a full curriculum vitae, 3) copies of educational certificates/thesis, 4) names and addresses of two referees, before October 31st 2011 to: Prof. Dr. Dr. h.c. V. Mosbrugger, Scientific Coordinator Biodiversity and Climate Research Centre, Senckenberganalge 25, D-60325 Frankfurt am Main, Germany. E-mail should be sent to Service and Administration: recruiting@senckenberg.de.

For scientific enquiries please contact Dr. Sonja Jaehnig (sonja.jaehnig@senckenberg.de), Dr. Carsten Nowak (carsten.nowak@senckenberg.de), or Dr. Steffen Pauls (steffen.pauls@senckenberg.de).

Doktorand zum Thema Functions of centrosomal proteins in maintaining genome stability (Heidelberg)

Our group is primarily interested in analysing design principles in mitotic spindle assembly. Faithful spindle formation and function is a prerequisite for proper cell division and ensures genomic stability. In turn, defects in spindle function will interfere with proper chromosome inheritance and are correlated with malignant transformation of cells, and the progression of human cancer diseases.
We recently finished a proteomic screen to survey which key factors are expressed de novo in a developing organism to reach competence for meiotic and mitotic spindle assembly. Interestingly, our screen identified several novel centrosomal proteins which seem to be rate limiting factors for de novo centrosome biogenesis, centrosome duplication, faithful spindle function, as well a and basal body assembly for primary cilia formation. The aim of a new project in the lab is to elucidate the function of these proteins at the molecular level. We are using a combination of biochemical assays in cell free extracts and siRNA-based approach in living human cells (Tegha-Dunghu et al., 2008; Reber et al., 2008) to identify and functionally characterise these novel centrosomal proteins.

Our laboratory is member of the recently founded DKFZ-ZMBH Alliance (http://www.dkfz-zmbh-allianz.de/index_en.html) and is receiving additional support from the award of a Start-Professorship (2010) by the Excellence Initiative of German Universities. The position for the described project is funded by a competitive fellowship for three years.

The ZMBH is equipped with all tools for cutting edge cell biology, including a state-of the art microscopy facility and excellent mass spectrometry unit. PhD students of the ZMBH are integrated into the HBIGS graduate school at the University of Heidelberg. Students in our group get excellent supervision in all technical and conceptual questions. Check out our homepage (http://www.zmbh.uni-heidelberg.de/gruss/default.shtml) to find out more.

We are looking for highly motivated individuals, who are seeking for a challenging project in basic science. Insight into protein biochemistry is required, and experience with imaging techniques is an advantage. The candidate should have a MSC in Biology, Molecular Biology, Biochemistry or Biophysics.

Postdoc Position in Electron Microscopy/Electron Beam Lithography (Greifswald, Germany)

A postdoc position at the Centre for Humoral Immune Reactions in Cardiovascular Disease (ZIK HIKE; www.hike-autoimmunity.de) at the Ernst-Moritz-Arndt-University Greifswald, Germany is available starting immediately. ZIK HIKE is a new interdisciplinary research centre supported through The Ministry of Education and Research 'BMBF' with the goal to explore the molecular basis of immune mediated cardiovascular diseases. The exquisitely equipped centre consists of closely collaborating groups from both the Faculty of Sciences and the Faculty of Medicine covering topics ranging from soft matter physics to cardiology. The position is affiliated with the newly established group 'Nanostructure', aiming at generating bio-mimetic model surfaces that evoke an immunogenic response. The tasks involve the generation of bio-functionalized nanostructured surfaces using electron beam lithography for the study of cell adhesion processes and the electron-microscopy based analysis of cellular !
 structures on these surfaces. For this purpose, a new, dedicated Zeiss Supra40VP electron microscope is available equipped with an e-beam lithography unit and a cryo-EM preparation system. Experience in electron microscopy of biological samples or electron beam lithography is an advantage.
The salary is paid according to the TVL E14.
Greifswald is a small and vibrant city at the Baltic Sea, which hosts one of Europe's most modern university clinics as well as a modern and expanding university campus. Daily life is dictated both by the high percentage of students and by the closeness to the sea.
Please send your CV describing your research experience, a list of publications, a letter of recommendation and the names and contact details of two references addressed to Dr. Mihaela Delcea via Dr. Hans-Peter Müller, ZIK HIKE Greifswald, preferentially mailto: hans-peter.mueller@uni-greifswald.de

PET/MRI physicist or engineer (PhD) (Dresden)

Vacancy Notice Reg.-No. 41E/2011

The Helmholtz-Zentrum Dresden-Rossendorf (HZDR) is operating one of the first worldwide available combined whole body PET/MR imaging systems. The system is used by an interdisciplinary team of scientists in the Department of Positron Emission Tomography of the Institute of Radiopharmacy together with colleagues from the University Hospital Dresden. The potential of this new technology for offering diagnostic information superior or complementary to conventional PET or PET/CT is substantial. Evaluation of this technology will be one of the central tasks of our group in the next years.

Our scientific focus is establishment of quantitative combined functional PET/MR imaging in oncology, notably for improvement of radiation treatment planning and therapy response control. In order to achieve this goal, substantial methodological work regarding optimized quantitative imaging procedures and data evaluation strategies will be necessary.

In this context, the Department of Positron Emission Tomography at the Institute of Radiopharmacy of the HZDR is looking for a

PET/MRI physicist or engineer (PhD)

to join our group. The contract is initially limited to 3 years.The salary is according to German Public Service classification (TVöD).

Prerequisites:

- good or very good marks in exams, diploma, and PhD thesis
- solid knowledge of basic PET and MRI physics
- preferably experience in the field of medical PET or MR imaging
- ability to adopt quickly to the new field and the given tasks
- adequate programming skills and experience with numerical data evaluation packages such as MATLAB, R, or similar
- willingness to work in an interdisciplinary group of physicists, computer scientists, physicians, and biochemists
- ability to work independently and to develop innovative solutions including publication of results

Tasks:

- Development of new data evaluation procedures for analysis of combined PET/MR investigations in oncology
- Development of optimized data acquisition protocols for quantitative functional PET/MR imaging with a focus on either the PET or the MRI side, depending on area of expertise of the candidate
- Contributions to on-going multi-disciplinary research projects in the context of functional PET/MR imaging in oncology in close collaboration with the University Hospital Dresden
- Participate in radiation protection and quality control related tasks at the PET/MR system

Please address your application (cover letter, CV, references) with the Registration-No. 41E/2011 until 15.11.2011, preferably via email, to: bewerbung@hzdr.de. Please attach pdf or word data.

For further information, please contact Prof. Dr. Jörg van den Hoff, Tel.: +49 351 260 2621, email: j.van_den_hoff@hzdr.de.

Women are explicitly invited to apply. Handicapped persons will be preferred in case of equal qualification.

Helmholtz-Zentrum Dresden-Rossendorf
Personnel department
P.O. Box 51 01 19
01314 Dresden, GERMANY

PhD position in Humoral Immune Reactions in Cardiovascular Diseases (Greifswald, Germany)

The Nanostructure group at ZIK HIKE is seeking enthusiastic and creative PhD students with an advanced degree MSc) in biology, biochemistry or related fields. Candidates should have a strong interest in interdisciplinary work ranging from biology via physics to medicine. High knowledge of protein structure and protein interactions is of advantage.

The aim of ZIK HIKE is to explore the molecular basis of immune mediated cardiovascular diseases as well as the mechanisms of immune reactions to biotherapeutics. The antigen structures that derive from native, recombinant and altered proteins will be biophysically analyzed and their impact on the cells of the immune system will be investigated.

ZIK HIKE consists of two research groups, cell response and nanostructure which strongly interact with each other and offers excellent research facilities for professional and personal development.

Starting date of the position: Immediately, latest in January of 2012. The salary will be 50% of TVL13.
Greifswald is a small and vibrant city at the Baltic Sea, which hosts one of Europe’s most modern university clinics as well as a modern and expanding university campus. Daily life is dictated both by the high percentage of students and by the closeness to the sea.
Interested candidates are asked to send their applications addressed to
Dr. Mihaela Delcea via Dr. Hans-Peter Müller, ZIK HIKE Greifswald, preferentially mailto:
hans-peter.mueller@uni-greifswald.de

PhD position in river ecology

The Leibniz-Institute for Freshwater Ecology and Inland Fisheries (IGB)invites applications for a

PhD position in river ecology.

The successful candidate will participate in an international project on assessment and restoration of river hydromorphology. The project is funded by the European Commission. He/she will study the interactions between hydromorphology and aquatic vegetation and the effects of aquatic plants on nutrient retention and oxygen budget.
The position is available from January 2012 and limited to 3 years.

Duties and responsibilities
•       analyses of effects of aquatic vegetation on flow conditions and particle transport
•       measurement of main processes like nutrient retention or re-aeration
•       contribution to studies on interactions between macrophytes, zoobenthos and fish

Requirements
•       completed studies in the field of aquatic ecology or hydraulic engineering
•       interest and expertise in ecology of aquatic macrophytes and/or hydrodynamics
•       good command in English

Salary is paid according to the TVoeD (50% position). In keeping with the IGB's policy regarding gender equity, female applicants are particularly encouraged. Disabled people with identical qualifications will be favoured.

Please send your applications / further inquiries to Dr. Jan Köhler (preferably by e-mail: koehler@igb-berlin.de) until October 31, 2011. Applicants should submit CV, a cover letter indicating research interests and experience, and the name and contact details of two referees.

Anfangsdatum: 29. September 2011

geschätzte Dauer: 3 Jahre

Bezahlung: TVoeD (50%)

The Leibniz-Institute for Freshwater Ecology and Inland Fisheries (IGB) is the largest freshwater ecology research institute in Germany (ww.igb-berlin.de). It is a member of the Forschungsverbund Berlin e.V. and the Leibniz-Association (www.wgl.de). The FVB manages 8 large research institutes in Berlin that have close links to all three universities in the German capital. IGB offers excellent laboratory and field facilities for interdisciplinary research, large-scale experimental facilities, and long-term research programs and data sets.

Postdoc in cell biology (Basel, Switzerland)

Applications are invited for a post-doctoral positions at the Institute of Biochemistry and Genetics, Dept. of Biomedicine at the University of Basel.
 
The interest of the lab is in spatio-temporal signaling dynamics during cell migration and neuronal differentiation using state of the art imaging techniques. In the current project, funded by the Swiss National Science Foundation,
a wide variety of projects are possible on the topics of spatio-temporal signaling dynamics during cell migration or neuronal differentiation or local mRNA translation during neurite outgrowth/repair.

We are looking for a talented and highly motivated cell biologist. Experience with live cell imaging, cell culture, computational approaches for image analysis are a plus. Excellent spoken and written English is required. This position will start on the 1st of december and last for at least 2 years. Salary is in accordance with the guidelines of the Swiss National Science Foundation.
 
Applications with a full CV, references and a cover letter should be submitted by email to Olivier Pertz :olivier.pertz@unibas.ch.
We are sorry to inform that applicants that are not short-listed for an interview will not be notified.

Website: http://biomedizin.unibas.ch/research/research-group-details/research/researchgroup/cell-migration-and-neuritogenesis/

PhD, Modulation of Autoimmunity (Borstel, Germany)

Graduate student position

A graduate student position is immediately available at the Department of Immunology and Cell Biology/Research Center Borstel for a highly motivated biologist interested in studying immune cell functions in autoimmune disease models in mice (supervisor - Dr. Zane Orinska).
The position will be within the newly established DFG Research Training Group “Modulation of Autoimmunity” (GRK1727). The major goal of the GRK1727 is the identification and evaluation of novel therapeutic targets and strategies for autoimmune diseases. We are seeking a candidate with a strong interest in translational immunological research, ideally with experience in cell biology, immunology and/or experimental disease models. Previous exposure to basic immunology and molecular biology techniques are required. We expect an ability to search and review the literature independently and work in a team-oriented environment.
The Research Center Borstel is an equal opportunities employer. Applications from female candidates are strongly encouraged. In case of compatible qualifications, preference will be given to people with disabilities. The Research Center Borstel is certified for the audit “Beruf und Familie” (“job and family”) and specifically promotes the compatibility of career and family.
The candidate should hold a diploma or masters in biology or biochemistry and preferably have some experience in animal experiments. The position will be available for three years.
Candidates should submit, under the keyword GRK1727, a CV and the name of three referees to:
Personalwesen
des Forschungszentrum Borstel
Parkallee 2
23845 Borstel
E-mail: cpaape@fz-borstel.de

PhD position / Immunology (Erlangen, Germany)

A PhD position will be available from 01.01.2012 at the Department of Infection Biology, Universitätsklinikum Erlangen. Our group studies the interaction of innate and adaptive immunity in murine models of infection and allergic inflammation. We are looking for a highly motivated candidate with a strong background in cellular and molecular immunology. Appointments will be for about 3 years and salary will be according to the German TV-L system (about 25.000 Euro/year before taxes).

The Universitätsklinikum Erlangen is an Equal Opportunity Employer / Affirmative Action Employer and has an affirmative action policy for the disabled.

Please send applications with CV and letters of recommendation to:

Prof. David Voehringer
Department of Infection Biology
Universitätsklinikum Erlangen
Friedrich-Alexander-Universität Erlangen-Nürnberg
Wasserturmstrasse 3-5
D-91054 Erlangen
Germany
phone office: +49(0)9131-85-32735
phone lab: +49(0)9131-85-32734
fax: +49(0)9131-85-32733
email: david.voehringer@uk-erlangen.de
website: www.infektionsbiologie.uk-erlangen.de

Regulation of the transcription factor PU.1 and on peripheral macrophage differentiation mechanisms (Muenster)

The Institute of Molecular Tumor Biology at the University of Münster invites applications for

POSTDOCTORAL and Ph.D. STUDENT POSITIONS

in the department of Molecular Stem Cell Biology, head Frank Rosenbauer, PhD.

Applicants are invited to join our newly established research team at the Institute of Molecular Tumor Biology, University of Münster, Germany. Our group has a long-term interest in elucidating molecular mechanisms that control hematopoietic stem cell function and leukemia development by investigating transcription factors and epigenetic pathways (Rosenbauer et al. 2004 Nature Genetics 36:624-30; Rosenbauer et al. 2006, Nature Genetics, 38: 27-37, Bröske et al. 2009 Nature Genetics 41: 1207-1215; Leddin et al. 2011, Blood, 117:2827-2838; Ghani et al. 2011; Blood in press.). We offer a highly interactive and stimulating environment as well as state of the art laboratory facilities.

We are currently looking for talented and highly motivated PhD students and postdoctoral fellows for projects on regulation of the transcription factor PU.1 and on peripheral macrophage differentiation mechanisms. We expect documented experience in molecular and cellular biology. Hands-on experience in working with laboratory mice is an advantage. A good command of the English language is required. Postdoctoral candidates should demonstrate a strong publication record in experimental hematopoiesis, molecular biology and/or cancer research.

The positions are initially for two years, but can be extended. They are funded according to the German TVL-system (group 13; for Ph.D. Students part time). Applications should include a full CV, a bibliography (for postdoctoral candidates) and the names of two referees.

The position will be open until filled. Applications should be sent by e-mail or regular mail to

Dr. Frank Rosenbauer
Institute of Molecular Tumor Biology (IMTB)
University of Münster
Robert-Koch-Str. 43
D-48149 Münster / Germany
E-mail: f.rosenbauer@mdc-berlin.de

Team assistant:
Jasmin Brands
E-mail: j.brands@uni-muenster.de
T +49-(0)251-83 55311
F +49-(0)251-83 55303

In case of similar qualification, competence and specific achievements, women will be considered on preferential terms within the framework of the legal possibilities. Handicapped candidates with equivalent qualifications will be given preference.

Postdoctoral position in myocardial physiology and tissue engineering (München)

Our research is focussed on the pathomechanisms of cardiac ischemia, and on therapeutic interventions including preconditioning, compliant reperfusion, and stem cell engraftment. The first-line targets comprise mechanotransduction, membrane integrity, and ion currents in ischemia. The experimental approach will be based on organotypic culture of human and mouse myocardium which enables analysis by up-to date methods of functional imaging, genetic manipulation, and electrophysiology. The development of stem cell culture into a similarly complex and functional tissue is one of our long-term goals.

The candidate should have an MD or PhD degree in Life Sciences with sound experience in experimental research. A special background in molecular biology, tissue engineering, or electrophysiology would be welcome. Motivation is required for the development of new experimental approaches, mentoring of doctoral fellows, and for lecturing tasks in all fields of Physiology.

The Walter-Brendel Centre is a translational research institute within the University Clinics of the Ludwig-Maximilians University of Munich. It is dedicated to cardiovascular research and offers a lively environment with central facilities of bioimaging and animal care, together with rich opportunities for clinical cooperation. We offer a post-doc position for 3 years that may be extended and should qualify for the german degree of 'Habilitation'.

Please send your application, curriculum vitae and references by email.

Prof. Andreas Dendorfer
andreas.dendorfer@med.uni-muenchen.de
Walter Brendel Zentrum, Ludwig-Maximilians-Universität
München

PhD in Biophysics: Computational Design of Proteins

PhD Position in Computational Biophysics, Erlangen

The research group for 'Computational Biology' at the University of  Erlangen-Nürnberg offers a PhD position. The project aims at the computational (re)design of proteins and ligands, in particular

- the design of proteins with modified pre-defined properties
- the development of novel methods for the prediction of binding affinities of peptidic ligands and drugs to proteins.

The candidate for this position is expected to have completed a  Master in chemistry or physics with a strong theoretical component, be strongly motivated and team-oriented. The position is limited to three years and is funded according to  the German E13 scale (50%). Work of the group for Computational Biology  is focused on the  prediction of structure, function and (nano)dynamics of membranes and  proteins.

http://www.biotechnik.nat.uni-erlangen.de/research/boeckmann/

Interested candidates should send their application by e-mail (*one* pdf  document containing letter, cv, certificates, references) to  Prof. Rainer Böckmann:
rainer.boeckmann@biologie.uni-erlangen.de

Methoden:
- molecular dynamics simulations
- Poisson-Boltzmann approaches
- machine learning algorithms

Anfangsdatum: 27. September 2011

geschätzte Dauer: 36 Monate

Bezahlung: 50% E13

Veröffentlichungen:
Alexander Benedix, Caroline M. Becker, Bert L. de Groot, Amedeo Caflisch, Rainer A. Böckmann
"Predicting Free Energy Changes Using Structural Ensembles"
Nature Methods 6 (2009) 3-4

Homepage: http://www.biotechnik.nat.uni-erlangen.de/research/boeckmann/

PhD in Interactions at Biological Membranes (Erlangen/Nürnberg)

PhD Position in Computational Biophysics, Erlangen

The research group for 'Computational Biology' at the University of  Erlangen-Nürnberg offers a PhD position. Projects involve the investigation of
- membrane-protein - lipid interactions using the method of molecular dynamics simulations
- the design of proteins with modified pre-defined properties
- the development of novel methods for the prediction of binding affinities of peptidic ligands and drugs to proteins.

The candidate for this position is expected to have completed a  Master in chemistry or physics with a strong theoretical component, be strongly motivated and team-oriented. The position is limited to three years and is funded according to  the German E13 scale (50%). Work of the group for Computational Biology  is focused on the  prediction of structure, function and (nano)dynamics of membranes and  proteins.

http://www.biotechnik.nat.uni-erlangen.de/research/boeckmann/

Interested candidates should send their application by e-mail (*one* pdf  document containing letter, cv, certificates, references) to  Prof. Rainer Böckmann:
rainer.boeckmann@biologie.uni-erlangen.de

PhD position: In vivo and in vitro analysis of molecular mechanisms of chromosome segregation (Heidelberg)

PhD position:
 “In vivo and in vitro analysis of molecular mechanisms of chromosome segregation”
Centre for Molecular Biology (ZMBH)
University of Heidelberg
The function and regulation of the mitotic spindle, which is the molecular machine that segregates the chromosomes, is one focus of our work. We use high-resolution microscopy, total internal reflection fluorescence (TIRF) microscopy, fluorescent recovery after photobleaching (FRAP), in vitro reconstitution assays and yeast genetics to unravel essential principals of chromosome segregation. Our group is optimally embedded into the life science campus of Heidelberg: we have close collaborations with groups from the German Cancer Research Centre (DKFZ; Dr. G. Pereira), the Center for Molecular Biology (ZMBH; Drs. S. Erhardt, O. Gruss and F. Melchior) and the Center of Organismal Studies (COS, Dr. J. Wittbrodt). This work is important because malfunctions in mitosis contribute to the development of cancer and chemicals that inhibit structural and regulatory components of mitosis are used as anti-cancer drugs.
We have an open PhD position: “In vivo and in vitro analysis of molecular mechanisms of chromosome segregation”.
The mitotic spindle is a dynamic machine that segregates the replicated chromosomes between the two daughter cells during cell division. In anaphase A shrinking kinetochore microtubules move the chromosomes towards the spindle poles. Concurrently, the spindle midzone is formed in the centre of the spindle where the conserved microtubule-bundling protein Ase1, kinesin motor proteins (Cin8 and Kip1), chromosomal passenger proteins (separase-Slk19), +TIPs (Bim1/EB1, Stu1/CLASP, Bik1/CLIP-170, Stu2/XMAP215) and signaling molecules (Aurora B kinase) localize 1-6. The spindle midzone stabilizes the anaphase spindle in all eukaryotic cells by crosslinking microtubules. It also drives spindle elongation in anaphase B and regulates cleavage furrow formation during cytokinesis in animal cells. The aim of this project is to study biochemical properties of spindle midzone proteins. Findings will be verified in the cell system using cell and molecular biology methods.

We are looking for a highly motivated PhD student with a strong background in biochemistry, cell biology or molecular biology. The successful candidate will be part of an international, highly motivated team of PhD students and postdocs that works at the forefront of scientific research. The PhD student will be a member of the Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology (HBIGS; http://www.hbigs.uni-heidelberg.de/).
The position is available from Oct. 2011-Sept. 2014.
Please apply to Prof. Elmar Schiebel, ZMBH, University of Heidelberg:
schiebel.elmar@zmbh.uni-heidelberg.de

Publications to this topic from the Schiebel group:

1       Pereira, G. & Schiebel, E. Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14. Science 302, 2120-2124 (2003).
2       Khmelinskii, A. & Schiebel, E. Assembling the spindle midzone in the right place at the right time. Cell Cycle 7, 283-286 (2008).
3       Khmelinskii, A., Lawrence, C., Roostalu, J. & Schiebel, E. Cdc14-regulated midzone assembly controls anaphase B. J. Cell Biol. 177, 981-993 (2007).
4       Khmelinskii, A., Roostalu, J., Roque, H., Antony, C. & Schiebel, E. Phosphorylation-dependent protein interactions at the spindle midzone mediate cell cycle regulation of spindle elongation. Dev. Cell 17, 244-256 (2009).
5       Roostalu, J., Schiebel, E. & Khmelinskii, A. Cell cycle control of spindle elongation. Cell Cycle 9 (2010).
6       Roostalu, J. et al. Directional switching of the kinesin Cin8 through motor coupling. Science 332, 94-99 (2011).

Investigation of Red blood cell dynamics with micropipette technique and circular dichroism spectrometry

The Institute of Bioengineering announces 2 opening positions for a internship/bachelor project or master thesis.

The two main activities in the projectswill be for the first: To study of the effects of environmental factors and different chemical agents on the red blood cells by using micropipette technique and for the second: To investigate structural transitions in proteins by circular dichroism spectrometry (FZ Jülich).

The successful applicant should possess sufficient knowledge in biochemistry and cell biology. Important are also social competences, motivation, organizational skills and responsibility.

The participant will learn and use a broad spectrum of laboratory techniques such as, micropipette aspiration technique, confocal microscopy, UV spectroscopy, osmometry, circular dichroism spectrometry and dynamic light scattering. Experience in laboratory routines is considered as an advantage.

Languages: English or German

The applicants should send their CVs and a letter of motivation to Mrs. Rasha Bassam, M.Sc. (bassam@fh-aachen.de) or can present themselves personally each Tuesday at 14.00 h in 01A13.

PhD/Postdoc in theoretical condensed matter physics (Frankfurt am Main)

The Institute for Theoretical Physics of Goethe University Frankfurt invites applications for the following vacancy

PhD or Postdoctoral Position

in theoretical condensed matter physics.

The contract will start on January 1st, 2012 with an initial duration of 12 months.

Salaries are according to the collective agreements on salary scales which apply at the Goethe University (E13, 50% or E13 100% TV-G-U).

We are seeking highly motivated individuals with a background in either ultracold atomic physics, quantum optics, strongly correlated electrons or numerical simulations of strongly interacting quantum many-particle systems. Furthermore, the successful candidates should have the capability to work independently and show dedication to the research projects of the group.

In the summer of 2005, Goethe University was awarded the basic certificate of the audit Family-Friendly University. Great importance is attached to the family-friendly structuring of the university work-stream. Employees will be supported in their efforts to combine their professional life with family duties. In this context, part-time employment and models of job-sharing are facilitated. Candidates returning to work after maternity/paternity leave are encouraged to apply for re-employment. Frankfurt University is committed to equal opportunities and selection on merit. Female candidates are especially encouraged to apply. Precedence will be given to handicapped candidates at equal qualification.

The deadline for applications is October 7th, 2011. Please send your curriculum vitae and a description of your research interests to:
Prof. Dr. Walter Hofstetter, http://itp.uni-frankfurt.de/cms/index.php?id=hofstetter, Institut für Theoretische Physik der Goethe-Universität, Campus Riedberg, Max-von-Laue-Str. 1, 60438 Frankfurt am Main.

PhD in Generation and characterization of warm-dense matter in the laboratory

The ExtreMe Matter Institute EMMI invites applications for a PhD student position in the field of experimental high energy density (HED) plasma physics in the newly established EMMI Fellow group for Plasma Physics.
We conduct state-of-the-art experiments to study the properties of matter at high energy density (>1Mbar), as found in astrophysical objects such as giant gas planets. These states of matter can be produced in the laboratory using high-intensity drivers (lasers, ion beams), by a variety of techniques (shock compression, heating with intense ion beams, laser-generated x-rays and particles). Characterization of the plasmas uses advanced techniques such as x-ray radiography, x-ray diffraction, x-ray Thomson scattering, inner-shell and bremsstrahlung spectroscopy.
Our experiments are conducted at large scale facilities, including GSI's intense heavy ion beam accelerator, the high-energy short-pulse laser PHELIX at GSI, the free-electron laser FLASH at DESY and the Petawatt laser Titan in Livermore, California.

Anfangsdatum: 25. September 2011

geschätzte Dauer: 3 years

Bezahlung: The position is supported with a stipend.

Veröffentlichungen:
A. L. Kritcher et al., Science 322, 69 (2008)
P. Neumayer et al., Phys. Rev. Lett. 105, 075003 (2010)
P. Neumayer et al., High Energy Dens. Phys. 5, 244 (2009)

The position is supported with a stipend. Structured PhD education is integrated in the Helmholtz Graduate School for Hadron and Ion Research HGS-HIRe (http://hgs-hire.de).

The ExtreMe Matter Institute EMMI at GSI has been established within the Helmholtz
Alliance “Cosmic Matter in the Laboratory”. EMMI provides a world-wide network
for interdisciplinary investigation of matter under extreme conditions – from
extremely hot matter of the early universe to ultra cold quantum gases.
Information about EMMI is available at http://www.gsi.de/emmi.

Post-doctoral Scientist in Virology for Laos project

Purpose:
- Coordinate the day-by-day activities of the virological LaoLux Laboratory in Vientiane, Laos. The candidate will be appointed for about 9 months/year in Laos
- Prepare the strategic planning of the research in close collaboration with the Dept of Immunology
- Manage the joint research projects of the Dept. of Immunology and the LaoLux Laboratory
- Provide specific expertise in the pertinent research areas

Activities and responsibilities of the LaoLuxLab (in collaboration with the HOD of the Dept of Immunology):
- Play a prominent role in the establishment of a new laboratory in South East Asia
- Establish the LaoLux virology group; contribute to the definition of the research priorities
- Scientific writing of articles for peer-reviewed international journals
- Develop scientific methodology and techniques adapted to the research project
- Train and supervise the technical staff, master students, PhD students
- Work in coordination with other post-doctoral scientists on their projects
- Contribute to defining research priorities with the HOD of the Dept of Immunology
- Present the work as well as results during laboratory meetings and at international meetings
- Communicate problems and suggestions for solutions in a clear way
- Participate in the societal dimension: dissemination of simplified research results to the general public (through articles, conferences, etc)
- Collaborations: establishment of a link between the laboratory and other partners, validation of the results, participation in the establishment of techniques that can eventually be transferred to other laboratories and cooperation with the institutions organizing the quality control

Main professional relations:
- Functional reporting line: project leader or researcher, HOD
- Internal: project leader, members of the project team, HOD
- External: dealing with external professional contacts as defined in his/her research projects

Scientific competence, work experience, diploma:
- PhD in life sciences (biology etc. ...)
- Experience in scientific work with and in developing countries
- Excellent time management, rigor, motivation, scientific creativity and originality, writing skills, conciseness, sense of priority and sense of human relations, punctual and reliable, stable health conditions
- A strong academic record and keen interest/knowledge in virology and infectious agents is essential
- Excellent proficiency in English and scientific writing skills are a must
- Knowledge of modern communication and computing skills

Weitere Einzelheiten zu diesem Angebot erfahren Sie unter
http://www.doktorandenboerse.info/suchen/angebot_ausgabe.php?Angebot_id=6955

Ph.D. student in Chemical Carcinogenesis (pharmacology/biochemistry/biology) (Sonstige)

Purpose:
The student will have to set-up and execute a PhD research project, focusing on the development of preventive and therapeutic post-exposure strategies.

Main activities:
- Conduct his/her research project under the best possible conditions in accordance with the conditions agreed between the university and the laboratory
- Work with a researcher who has set up a research project and participate in the drafting of scientific articles about the ongoing project
- Scientific writing of articles for peer-reviewed international journals
- Carry out experiments in the laboratory
- Develop a scientific methodology and techniques adapted to the research project
- Present the work as well as results during laboratory meetings and at international meetings
- Communicate problems and suggestions for possible solutions in a clear way

Weitere Einzelheiten zu diesem Angebot erfahren Sie unter
http://www.doktorandenboerse.info/suchen/angebot_ausgabe.php?Angebot_id=6951

Post-doctoral Scientist in Proteomics

Purpose:
- Project manager of the proteomic platform
- Responsible for the development of new and ongoing projects leading to publications
- Responsible for the development and writing of new projects in the field of proteomic together with the HOD

Main activities:
- Establish the link between proteomics and other projects in the different fields of the laboratory
- Collaborate with other scientists and you will provide original proteomics approaches.
- Develop new collaborations within and outside the CRP-Santé on a national and international level together with the HOD
- Present results in proteomics at meetings and congresses

Main professional relations:
- Functional reporting line: project leader or researcher, HOD
- Internal: project leader, members of the project team, HOD
- External: dealing with external professional contacts as defined in his/her research projects

The candidate must have the following skills:
- Identification and characterization of proteins: Protein mass fingerprint and de novo sequencing techniques (MALDI TOF/TOF and LC-MS ion trap) / Two dimensional gel electrophoresis and two dimensional Western blot /
- Data interpretation via bioinformatics tools: Bruker and Agilent software / Protein data bases with MASCOT / One area of life sciences relevant to the scientific activities of the department Skills in virology are considered an asset.

Scientific competence, work experience, diplomas and other requirements:
- PhD in the field of proteomics or a related field
- Strong background in mass spectrometry and related techniques, good knowledge in bioinformatics
- Experience in project management
- Excellent supervising, management and communication skills
- Ability to work in a team environment and interact with a multi-disciplinary team of scientists
- Passionate, creative, dynamic, result oriented
- Proficiency in English and good scientific writing skills are a must.

Weitere Einzelheiten zu diesem Angebot erfahren Sie unter
http://www.doktorandenboerse.info/suchen/angebot_ausgabe.php?Angebot_id=6956

1 Diploma/Master thesis (Zoology) entitled Prevalence and distribution of Culicidae species in Luxembourg

Purpose:
Carry out his/her MSc project

Main activities:
- Student majoring in Zoology to perform a survey on Culicidae species in Luxembourg.
- The candidate will investigate the prevalence and distribution of mosquitoes from various collection sites inside of Luxembourg.
- The project will involve sample collection, identification of species by morphological means, and thorough analysis of geographical distribution patterns.
- The goal of this project is to determine the endemicity, abundance and distribution of Culicidae species with regard to the emergence of infectious mosquito-borne diseases in Europe.

Methoden:
Scientific competence, work experience and diploma:
- Undergraduate degree in Biology (Bachelor)
- A strong background in Zoology/Entomology as well as experience in morphological identification of insect species is required
- Rigor, motivated, scientific creativity and originality, writing skills, conciseness, sense of priority and sense of human relations
- Proficiency in English and good scientific writing skills are a must.

Anfangsdatum: 1. Dezember 2011

geschätzte Dauer: 2-12 months

Homepage: http://www.immunology.lu ; www.crp-sante.lu

Candidates must apply in English with a letter of motivation, a detailed and complete CV with personal, academic and professional information, scanned diplomas with marks,  Laboratory experience including techniques, Computer experience including programmes, networks, Language skills (using the European Self Assessment Guide), Peer-reviewed scientific publications, Oral presentations, meeting participations, posters, abstracts

Address of correspondence (ideally by e-mail):
Institute of Immunology
Centre de Recherche Public de la Santé / National Public Health Laboratory
Prof. Dr. Claude P. Muller
P. O. Box 1102
L-1011 Luxembourg
Tel: +352 490604220
Fax: +352 490686
claude.muller@LNS.ETAT.LU
www.immunology.lu and/or www.crp-sante.lu

Ph.D. student in Chemical Carcinogenesis (pharmacology/biochemistry/biology)

Purpose:
The student will have to set-up and execute a PhD research project, focusing on the development of preventive and therapeutic post-exposure strategies.

Specificity:
He/she will receive a working contract funded by a Luxembourg's AFR fellowship. The student is expected to participate in the preparation of this proposal.

Main activities:
- Conduct his/her research project under the best possible conditions in accordance with the conditions agreed between the university and the laboratory
- Work with a researcher who has set up a research project and participate in the drafting of scientific articles about the ongoing project
- Scientific writing of articles for peer-reviewed international journals
- Carry out experiments in the laboratory
- Develop a scientific methodology and techniques adapted to the research project
- Present the work as well as results during laboratory meetings and at international meetings
- Communicate problems and suggestions for possible solutions in a clear way

Methoden:
Scientific competence, work experience and diploma:
- Required diploma: MS or equivalent in biology/biochemistry/immunology
- A strong academic record and a keen interest/ knowledge in chemical carcinogenesis or in a relevant area of pharmacology, analytical chemistry, cell biology or related fields are essential
- Rigor, motivated, scientific creativity and originality, writing skills, conciseness, sense of priority and sense of human relations, punctual and reliable, time-management
- Knowledge of modern communication and computing skills
- Proficiency in English and good scientific writing skills are a must.

Anfangsdatum: 1. Dezember 2011

geschätzte Dauer: 3-4Y

Homepage: http://www.immunology.lu ; www.crp-sante.lu

Candidates must apply in English with a letter of motivation, a detailed and complete CV with personal, academic and professional information, scanned diplomas with marks,  Laboratory experience including techniques, Computer experience including programmes, networks, Language skills (using the European Self Assessment Guide), Peer-reviewed scientific publications, Oral presentations, meeting participations, posters, abstracts

Address of correspondence (ideally by e-mail):
Institute of Immunology
Centre de Recherche Public de la Santé / National Public Health Laboratory
Prof. Dr. Claude P. Muller
P. O. Box 1102
L-1011 Luxembourg
Tel: +352 490604220
Fax: +352 490686
claude.muller@LNS.ETAT.LU
www.immunology.lu and/or www.crp-sante.lu

PhD in vivo and in vitro analysis of molecular mechanisms of chromosome segregation (Heidelberg)

PhD position:
 “In vivo and in vitro analysis of molecular mechanisms of chromosome segregation”
Centre for Molecular Biology (ZMBH)
University of Heidelberg
The function and regulation of the mitotic spindle, which is the molecular machine that segregates the chromosomes, is one focus of our work. We use high-resolution microscopy, total internal reflection fluorescence (TIRF) microscopy, fluorescent recovery after photobleaching (FRAP), in vitro reconstitution assays and yeast genetics to unravel essential principals of chromosome segregation. Our group is optimally embedded into the life science campus of Heidelberg: we have close collaborations with groups from the German Cancer Research Centre (DKFZ; Dr. G. Pereira), the Center for Molecular Biology (ZMBH; Drs. S. Erhardt, O. Gruss and F. Melchior) and the Center of Organismal Studies (COS, Dr. J. Wittbrodt). This work is important because malfunctions in mitosis contribute to the development of cancer and chemicals that inhibit structural and regulatory components of mitosis are used as anti-cancer drugs.
We have an open PhD position: “In vivo and in vitro analysis of molecular mechanisms of chromosome segregation”.
The mitotic spindle is a dynamic machine that segregates the replicated chromosomes between the two daughter cells during cell division. In anaphase A shrinking kinetochore microtubules move the chromosomes towards the spindle poles. Concurrently, the spindle midzone is formed in the centre of the spindle where the conserved microtubule-bundling protein Ase1, kinesin motor proteins (Cin8 and Kip1), chromosomal passenger proteins (separase-Slk19), +TIPs (Bim1/EB1, Stu1/CLASP, Bik1/CLIP-170, Stu2/XMAP215) and signaling molecules (Aurora B kinase) localize 1-6. The spindle midzone stabilizes the anaphase spindle in all eukaryotic cells by crosslinking microtubules. It also drives spindle elongation in anaphase B and regulates cleavage furrow formation during cytokinesis in animal cells. The aim of this project is to study biochemical properties of spindle midzone proteins. Findings will be verified in the cell system using cell and molecular biology methods.

We are looking for a highly motivated PhD student with a strong background in biochemistry, cell biology or molecular biology. The successful candidate will be part of an international, highly motivated team of PhD students and postdocs that works at the forefront of scientific research. The PhD student will be a member of the Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology (HBIGS; http://www.hbigs.uni-heidelberg.de/).
The position is available from Oct. 2011.

Publications to this topic from the Schiebel group:

1       Pereira, G. & Schiebel, E. Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14. Science 302, 2120-2124 (2003).
2       Khmelinskii, A. & Schiebel, E. Assembling the spindle midzone in the right place at the right time. Cell Cycle 7, 283-286 (2008).
3       Khmelinskii, A., Lawrence, C., Roostalu, J. & Schiebel, E. Cdc14-regulated midzone assembly controls anaphase B. J. Cell Biol. 177, 981-993 (2007).
4       Khmelinskii, A., Roostalu, J., Roque, H., Antony, C. & Schiebel, E. Phosphorylation-dependent protein interactions at the spindle midzone mediate cell cycle regulation of spindle elongation. Dev. Cell 17, 244-256 (2009).
5       Roostalu, J., Schiebel, E. & Khmelinskii, A. Cell cycle control of spindle elongation. Cell Cycle 9 (2010).
6       Roostalu, J. et al. Directional switching of the kinesin Cin8 through motor coupling. Science 332, 94-99 (2011).

Post-Doctoral Position in Cancer Research ,Group of Ingrid Hoffmann,Heidelberg, Germany

A post-doctoral position is available in the laboratory of Dr. Ingrid Hoffmann at the German Cancer Reserach Center in Heidelberg, Germany. The position is funded initially for two years (salary according to TVL-E13).
We are working on the regulation of the centrosome in mammalian cells (Cizmecioglu et al., 2010, JCB 191, 731-9; Puklowski et al., 2011, NCB 13, 1004-9). Having the correct number of centrosomes is crucial for proper chromosome segregation during cell division and for the prevention of aneuploidy, a hallmark of many cancer cells. Like DNA, centrosomes are duplicated only once per cell cycle. Errors in centrosome duplication lead to cells with too many or too few centrosomes. The biochemical pathways underlying centriole duplication are largely unknown.
The aim of the project is to identify and characterize substrates of the master regulator of centrosome duplication, using SILAC and biochemical techniques. The project will aim at characterizing the identified proteins in centrosome duplication and to analyze their regulation by Plk4.
We are seeking highly motivated PhD candidates with experience in molecular biological and biochemical techniques. Please send your CV, publication list, certificates and the names and addresses of at least two referees to
PD Dr. Ingrid Hoffmann, DKFZ (F045), E-mail: Ingrid.Hoffmann@DKFZ.de, Tel: 06221-424909
Group Homepage: http://www.dkfz.de/en/f045/index.php

PhD position "Mitosis" ,Heidelberg, Germany

PhD position “Mitosis”
Centre for Molecular Biology (ZMBH) Heidelberg University
and The Paterson Institute for Cancer Research

The groups of E. Schiebel at the Center for Molecular Biology (ZMBH) (http://www.zmbh.uni-heidelberg.de/ schiebel/default.shtml), Heidelberg University, Germany and I. Hagan at the Paterson Institute, University of Manchester, UK (http://www.paterson.man.ac.uk/) have long-lasting interests in the molecular analysis of mitosis (for publications see below 1-12).
We have an open PhD position: “Cell cycle regulation of centrosome duplication”.
Centrosomes are important organelles that organize microtubules, regulate cytokinesis and are associated with cell cycle regulators. Centrosomes become duplicated only once during the cell cycle, however, the molecular mechanisms that coordinate centrosome duplication with the cell cycle are still largely unknown. Here, we use budding and fission yeast as model organisms to study centrosome duplication. A key question of our research is how the yeast centrosome becomes embedded into the nuclear envelope after its duplication and how centrosome duplication is coordinated with the cell cycle machinery. We will compare conserved principals in both model organisms.
We use advanced microscopy (FRAP, FRET, photoactivation), electron microscopy, in vitro reconstitution assays with purified proteins and yeast genetics to unravel essential principals of mitosis. PhD students have access to several high-end facilities at Heidelberg University and The Paterson Institute.
We are looking for a highly motivated PhD student with a strong background in biochemistry, cell biology or molecular biology. Successful candidates will be part of an international, highly motivated team of PhD students and postdocs that works at the forefront of scientific research. The PhD student will be a member of the Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology (HBIGS; http://www.hbigs.uni-heidelberg.de/) and the GRK1188 (http://bzh.db-engine.de/default.asp?lfn=en4036). The PhD student will spend time in Heidelberg and Manchester to work at both institutions. The PhD position is available from October 2011-Sept. 2014.

Please send applications to HBIGS (online application) or E. Schiebel (schiebel.elmar@zmbh.uni-heidelberg.de).

Selected publications of the Hagan and Schiebel groups:

1       Khmelinskii, A., Keller, P. J., Lorenz, H., Schiebel, E. & Knop, M. Segregation of yeast nuclear pores. Nature 466, (7305):E7301 (2010).
2       Pereira, G. & Schiebel, E. Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14. Science 302, 2120-2124 (2003).
3       Khmelinskii, A., Roostalu, J., Roque, H., Antony, C. & Schiebel, E. Phosphorylation-dependent protein interactions at the spindle midzone mediate cell cycle regulation of spindle elongation. Dev. Cell 17, 244-256 (2009).
4       Mardin, B. R. et al. Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction. Nat. Cell Biol. 12, 1166-1176, doi:ncb2120 [pii]10.1038/ncb2120 (2010).
5       Roostalu, J. et al. Directional switching of the kinesin Cin8 through motor coupling. Science 332, 94-99, doi:science.1199945 [pii]10.1126/science.1199945 (2011).
6       Kupke, T. et al. Targeting of Nbp1 to the inner nuclear membrane is essential for spindle pole body duplication. EMBO J, doi:emboj2011242 [pii]10.1038/emboj.2011.242 (2011).
7       Grallert, A. et al. S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner. Genes Dev. 20, 2421-2436, doi:20/17/2421 [pii]10.1101/gad.381306 (2006).
8       Grallert, A. & Hagan, I. M. Schizosaccharomyces pombe NIMA-related kinase, Fin1, regulates spindle formation and an affinity of Polo for the SPB. EMBO J 21, 3096-3107 (2002).
9       Grallert, A., Krapp, A., Bagley, S., Simanis, V. & Hagan, I. M. Recruitment of NIMA kinase shows that maturation of the S. pombe spindle-pole body occurs over consecutive cell cycles and reveals a role for NIMA in modulating SIN activity. Genes Dev. 18, 1007-1021 (2004).
10      Petersen, J. & Hagan, I. M. Polo kinase links the stress pathway to cell cycle control and tip growth in fission yeast. Nature 435, 507-512, doi:nature03590 [pii]10.1038/nature03590 (2005).
11      Tamm, T. et al. Brr6 drives the S. pombe spindle pole body nuclear envelope insertion/extrusion cycle. . J. Cell Biol. in press (2011).
12      Tallada, V. A., Tanaka, K., Yanagida, M. & Hagan, I. M. The S. pombe mitotic regulator Cut12 promotes spindle pole body activation and integration into the nuclear envelope. J. Cell Biol. 185, 875-888, doi:jcb.200812108 [pii]10.1083/jcb.200812108 (2009).

PhD in The role of human Cdc14 phosphatases in DNA repair and aging (Heidelberg)

PhD position
The role of human Cdc14 phosphatases in DNA repair and aging
Centre for Molecular Biology (ZMBH)
University of Heidelberg

Cdc14 belongs to a family of highly conserved dual-specificity phosphatases that are present in a wide range of organisms from yeast to human cells. Human Cdc14B is implicated in the DNA damage checkpoint activation, DNA repair and aging 1-4. However, little is known about the substrates of hCdc14A and hCdc14B and their regulation. The goal of this thesis is to study the regulation of hCdc14B in response to DNA damage and aging, to identify substrates of hCdc14B and to unravel phosphatases that may function concertedly with hCdc14B. The successful candidate will perform siRNA screens using human Cdc14A/B-/- cell lines for phosphatases with functions that overlap with hCdc14A/B, identify interacting proteins that regulate hCdc14B in the nucleolus and analyze the pathways that promote the release of hCdc14B from the nucleolus in response to DNA damage.

We are looking for a highly motivated PhD student with a strong background in biochemistry, cell biology or molecular biology. Successful candidates will be part of an international team of highly motivated PhD students and postdocs that works at the forefront of scientific research (http://www.zmbh.uni-heidelberg.de/schiebel/default.shtml). The PhD student will be a member of the Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology (HBIGS; http://www.hbigs.uni-heidelberg.de/).

Time period: 1 Oct. 2011 – 30 Sept. 2014

Please send written applications (CV, letter of motivation, transcripts) with 2-3 names of referees to Prof. Dr. Elmar Schiebel, ZMBH, Uni Heidelberg (schiebel.elmar@zmbh.uni-heidelberg.de).
Literature
1       Mocciaro, A. et al. Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair. J. Cell Biol. 189, 631-639, doi:jcb.200910057 [pii]10.1083/jcb.200910057 (2010).
2       Mocciaro, A. & Schiebel, E. Cdc14: a highly conserved family of phosphatases with non-conserved functions? J. Cell Sci. 123, 2867-2876, doi:123/17/2867 [pii]10.1242/jcs.074815 (2010).
3       Bassermann, F. et al. The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Cell 134, 256-267 (2008).
4       Wei, Z. et al. Early onset aging and defective DNA damage response in Cdc14b-deficient mice. Mol. Cell. Biol., doi:MCB.01330-10 [pii]10.1128/MCB.01330-10 (2011).

Scientific Programmer in web framework and climate simulation data handling,Hamburg,Germany

The Max Planck Institute for Meteorology (MPI-M) is a multidisciplinary centre for climate research located in Hamburg, Germany. It has an internationally recognised reputation in climate modelling. Within the project EUDAT (EUropean DATa) funded by the European Commission under Grant agreement no 283304 we are looking for a

Scientific Programmer (m/f; 2011-22)

with a strong background in computational science, web frameworks and / or climate simulation data handling. Within the department “The Atmosphere in the Earth System”, the successful applicant will join a team that develops, maintains, improves, and uses the software package “Climate Data Operators” (CDOs).

His/her task will be to adapt the CDOs to their use in web environments and frameworks as they will be developed and used in EUDAT. Performance and scal-ability issues will be of major importance, but also usability and meta-data administration.
A degree in applied mathematics, meteorology, oceanography, physics, computa-tional science or a related area is required. Excellent programming skills in Java, C++, C, and scripting languages (shells and Python) as well as knowledge in Web Services and Frameworks and associated areas are essential. Our development systems are Unix/Linux based.

The MPI-M is located in the heart of one of Europe’s most liveable and vibrant cit-ies.  It provides a highly international and interdisciplinary environment for conducting scientific research as well as access to state-of-the-art scientific facilities. For further information, please contact Reinhard Budich (reinhard.budich(at)zmaw.de) or Uwe Schulzweida (uwe.schulzweida(at)zmaw.de). Applications should be for-warded to the address indicated below.

The position is offered for two years, starting immediately. Payment will be in accordance with German public service positions (TVoeD E13), including extensive social security plans. The conditions of employment, including upgrades and dura-tion, follow the rules of the Max Planck Society for the Advancement of Sciences and those of the German civil service. The Max Planck Institute for Meteorology seeks to increase the number of female scientist and encourages them to apply. Handicapped persons with comparable qualifications receive preferential status.

The selection process will start on 14 October 2011 and will continue until the positions are filled. Please submit a letter of interest, curriculum vitae, and the names, addresses, and telephone numbers of two references via E-Mail:
jobs@vw.mpimet.mpg.de (pdf-attachments max. 2 MB only), or by post to:

Max Planck Institute for Meteorology
Administration (2011-22)
Bundesstrasse 53
D-20146 Hamburg, Germany

Post-Doc Position Molecular Virology Species barriers of hepatitis C virus replication

Job Advertisement Nr. 51/2011

The TWINCORE – Centre for Experimental and Clinical Infection Research offers a post-doc position in the research group of Prof. Dr. Thomas Pietschmann. Funding by the European Research Council is available for up to five years.

Post-Doc Position Molecular Virology
Species barriers of hepatitis C virus replication

RNA viruses are responsible for important acute, chronic as well as emerging human infections. While some of these viruses – like for instance the hepatitis C virus (HCV) – are highly species-specific, others (e.g. Dengue Virus and West Nile Virus) infect different host species. The reasons why some of these viruses are highly species-specific whereas others have a broad tropism are poorly understood. The key objective of the project is to precisely define all factors determining the species barrier to HCV replication in mouse liver cells. The inability of HCV to propagate in non-human cells may be due to lack or genetic incompatibility of essential cellular replication co-factors and/or due to operation of antiviral restriction mechanisms effectively suppressing viral replication in non-human host cells. For that reason we will identify and characterize both essential host dependency and restriction factors which are relevant to species-specific replication of HCV.

Your qualification:
Candidates should have successfully completed a university degree in molecular biology or a related subject and should have acquired a PhD in virology. He/She should have a strong background and deep interest in virology and cell biology. Experience with plus strand RNA viruses, cell-imaging techniques, genetic screenings and analysis of protein-protein interactions are of advantage. We look for creative and highly motivated individuals who wish to conduct research in an international and interdisciplinary team of scientists.

Severely disabled applicants will be favoured if they are equally qualified.

Starting date:          01.01.2012
                       The contract will be for two years with the possibility for extension

Salary:                 TVöD E13 + bonus to E14

Published:              19.09.2011
Closing date:           21.10.2011

Please send your application (closing date is October 21st 2011) containing CV, publication record, a short description of your previous and future research interests (up to one page), and two academic reference addresses with refer to code 51/2011 to:
Helmholtz Centre for Infection Research, Dept. of Human Ressources, Inhoffenstr. 7,
38124 Braunschweig, Germany
or by e-mail: JobsHZI@helmholtz-hzi.de

For further information, please contact:
Prof. Dr. Thomas Pietschmann
Telephone: +49 511 22 00 27-130
or by Email: thomas.pietschmann@twincore.de
Web: http://www.twincore.de/

PhD in Supramolecular Surface Chemistry and Electronic Structure

Two Ph.D. (Doktorarbeit) projects are being offered in the field of supramolecular frameworks surface and interface chemistry. Diploma theses are also possible. These projects are located at the University of South Florida (USF) and are a collaboration between the electrical engineering, chemistry and physics programs. The focus of the projects centers around the growth of metal organic framework systems on surfaces, and the investigation of the related surface chemistry and interface electronic structure. A major focus is on the development of self-assembling semiconducting frameworks structures that can be used in photovoltaic and electronic device applications. The preparative and analytical techniques include self assembly in solution, electrospray thin film deposition in vacuum, photoemission spectroscopy/inverse photoemission spectroscopy, scanning probe microscopy, and state of the art electron microscopies. Successful applicants are self-motivated individuals with dip
 loma or masters degrees in chemistry, physics or engineering.  They have the ability to collaborate in an interdisciplinary team. The positions are also open to University of Applied Sciences (Fachhochschule) graduates in science and engineering disciplines.
The University of South Florida is one of the largest metropolitan universities of the US serving over 40,000 students and is located in Tampa, on the West Coast of Florida. Tampa features a lively cultural scene combined with the sunny Florida beach-lifestyle. Interested applicants should email (in English or German) a curriculum vitae, brief statement of research interests and names/e-mail/phone numbers of at least two references to Prof. Rudy Schlaf, Dept. of Electrical Engineering, University of South Florida, Tampa, FL 33620, USA, e-mail: schlaf@eng.usf.edu, web: http://rsl.eng.usf.edu/, Voice: +1-813-974-8463, FAX:+1-813-974-5250. Informal inquiries about the opportunities are welcome! USF is an equal opportunity employer. Applications of female and minority students are especially encouraged.

Anfangsdatum: 3. Januar 2011

geschätzte Dauer: 3 Jahre

Bezahlung: $20k+Studiengebühren

Homepage: http://rsl.eng.usf.edu/

PhD in Supramolecular Surface Chemistry and Electronic Structure

Two Ph.D. (Doktorarbeit) projects are being offered in the field of supramolecular frameworks surface and interface chemistry. Diploma theses are also possible. These projects are located at the University of South Florida (USF) and are a collaboration between the electrical engineering, chemistry and physics programs. The focus of the projects centers around the growth of metal organic framework systems on surfaces, and the investigation of the related surface chemistry and interface electronic structure. A major focus is on the development of self-assembling semiconducting frameworks structures that can be used in photovoltaic and electronic device applications. The preparative and analytical techniques include self assembly in solution, electrospray thin film deposition in vacuum, photoemission spectroscopy/inverse photoemission spectroscopy, scanning probe microscopy, and state of the art electron microscopies. Successful applicants are self-motivated individuals with dip
 loma or masters degrees in chemistry, physics or engineering.  They have the ability to collaborate in an interdisciplinary team. The positions are also open to University of Applied Sciences (Fachhochschule) graduates in science and engineering disciplines.
The University of South Florida is one of the largest metropolitan universities of the US serving over 40,000 students and is located in Tampa, on the West Coast of Florida. Tampa features a lively cultural scene combined with the sunny Florida beach-lifestyle. Interested applicants should email (in English or German) a curriculum vitae, brief statement of research interests and names/e-mail/phone numbers of at least two references to Prof. Rudy Schlaf, Dept. of Electrical Engineering, University of South Florida, Tampa, FL 33620, USA, e-mail: schlaf@eng.usf.edu, web: http://rsl.eng.usf.edu/, Voice: +1-813-974-8463, FAX:+1-813-974-5250. Informal inquiries about the opportunities are welcome! USF is an equal opportunity employer. Applications of female and minority students are especially encouraged.

Anfangsdatum: 3. Januar 2011

geschätzte Dauer: 3 Jahre

Bezahlung: $20k+Studiengebühren

Homepage: http://rsl.eng.usf.edu/

Grid-computing/Cloud-computing positions at LRZ (Garching near Munich)

The Leibniz Supercomputing Centre is one of the three national High
Performance Computing centers in Germany and operates one of the most
powerful supercomputers in Europe. The fastest computer in Europe, the
SuperMUC, will become operational at the LRZ next year. Within
national and European projects we provide scientists throughout the
whole world with an up-to-date Grid computing infrastructure for data,
information, and computing services.

In the field of Grid-computing/Cloud-computing the Leibniz
Supercomputing Centre in Garching (Munich) is looking for

three scientific staff members
(university post graduate degree; master's degree or equivalent).

You will contribute to national and European research projects
(www.d-grid.de, www.cern.ch/lcg, www.prace-project.eu, www.egi.eu,
www.ige-project.eu), some of which are headed by the LRZ, and will be
working in a multifaceted field on a variety of tasks aimed at
achieving long-lasting results. You will collaborate with the leading
high performance computing centers in Europe and will work with the
main developers of Globus in the USA. The three positions being filled
are in the areas of "Monitoring of Grid-Infrastructures", "Grid
Operation", and "Grid Middleware Globus", respectively. The solutions
which you develop and implement will be applied in large-scale
European projects.

In particular, you will take responsibility for some of the following
tasks (either as an individual or as part of a team):

* integration of new information providers into the LRZ-developed DMON
software
* development of monitoring concepts
* development of monitoring solutions for Globus middleware
* developing Globus middleware
* scouting new technologies and development, focusing on using Cloud
Computing and virtualization techniques in Grid computing
* representing LRZ at national and international policy bodies
* liaison to scientific communities (e.g., astrophysics, particle
physics, geophysics, climatology, medical and life sciences) depending
on your scientific orientation
* operation of Grid infrastructure
* presenting research results in meetings, work shops, symposia, and
conferences (primarily in English)
* installing middleware for the management of resources in the grid
* facilitating training on the usage of Grid software
* monitoring computing budgets and statistics
* supporting users executing Grid projects
* administering grid resources for data storage and computation,
firewalls, configuration management
* administering user projects in the Grid area
* writing reports, deliverables, and documentation (primarily in
English)
* maintaining our web Grid portal and our internal wiki
* programming in C, C++, Java, Python, Perl, shell scripting

You should have the following qualifications:
* a post graduate university degree in a scientifically oriented
subject (computer science, mathematics, physics, etc.) with an above
average GPA
* experience with UNIX/Linux based systems
* programming knowledge with shell and scripting languages (Perl,
Python, etc.) and a high level programming language (C, C++, or Java)
* experience with Grid middleware, notably Globus, is a plus but not a
must
* interest in and enjoyment of project oriented research and
scientific work
* willingness to participate in symposia, conferences and workshops,
also outside of Germany (e.g., Bologna, Paris, Barcelona, Amsterdam,
USA, etc.)
* good speaking and writing skills in English
* a basic knowledge of the German language
* initiative, capacity for teamwork, and creativity.

The following skills would be helpful:

* familiarity with Grid Middleware: Globus, gLite, or UNICORE
* mastery of HTML and CSS
* familiarity with Eclipse and Plugins
* knowledge of common monitoring tools such as Nagios, Ganglia, Inca, etc.
* experience with installation and configuration of Apache Webserver, Tomcat, REST interfaces
* familiarity with the configuration of firewalls.

Due to its state-of-the-art computing facilities and its proximity to
the Munich universities, LRZ offers a very stimulating and innovative environment. Progressive policies such as flexible working hours
support the combination of work and family life. The free choice of
your favorite operating system (Mac, Linux or Windows; laptop or
desktop) will contribute to an enjoyable work experience at LRZ.

We offer you a pleasant and easygoing work environment in an
internationally recognized research team with many years of experience
that you can draw on for support, while also having ample
opportunity to work independently and follow your individual
preferences. In addition you have the option of pursuing advanced
training or a doctorate (PhD) at one of the many nearby universities.
German is the official language at the LRZ, so German language skills
are beneficial, but English is predominantly spoken in our
multinational team.

Salary is determined by TV-L. The position is time-limited, initially
to two years. Following the institute's goal of equal opportunity,
qualified women are strongly encouraged to apply. Disabled
persons will be hired preferentially over others with equal
qualifications.

Please submit your application with resume (C.V.), university
transcripts, and letters of recommendation by September 25th, 2011 to:

Leibniz Supercomputing Centre           or via email to:
Mrs. Hannelore Apel                     apel@lrz.de
- keyword: Grid computing - (2011/01)
Boltzmannstr. 1
85748 Garching near Munich

For submissions via email (preferred!) we kindly ask you to send your\
application as a single Word, postscript, or PDF document (not many
individual files). Documents can only be returned if a self-addressed
envelope with sufficient postage is included. Therefore it is best to
send only copies of your documents. Protective covers or wrappers can
be omitted.

For further information please contact:

Dr. Helmut Heller (Tel: 089/35831-8823, Email: heller@lrz.de) or
Dr. Anton Frank (Tel: 089/35831-7841, Email: frank@lrz.de).

A Postdoc position is available in the Department of Anesthesiology and Critical Care Medicine at the University of Münster in Germany

Postdoc position
Ref.: 5281

A Postdoc position is available in the Department of Anesthesiology and Critical Care Medicine at the University of Münster (Münster, Germany) to study the mechanisms of neutrophil activation in mouse models of inflammation. One focus of the work will be defining which molecules are involved in E-selectin mediated neutrophil activation leading to integrin activation, in vitro and in vivo.

These studies will utilize various techniques in cell biology, molecular biology and biochemistry, including intravital microscopy studies on neutrophil rolling and adhesion in mice, flow cytometry, flow chamber assays, immunofluorescence microscopy, protein-protein interaction, retroviral transfection of bone marrow cells, and generation of bone marrow chimeras.

This position will be in the lab of a young Principle Investigator (PI). The PI is committed to the applicants career development by creating an exciting and dynamic research environment with state-of-the-art technologies, encouraging the preparation of research papers, the participation at (inter)national meetings, and the submission of independent grant applications. A technician will be assigned to the applicant for support in laboratory work. A weekly joint lab meeting with scientists from various laboratories and a good international network of collaborators provides a unique opportunity to exchange ideas. Candidates must have a Ph.D. and/or MD degree. There are no specific requirements with regard to the applicant’s technical skills, but he/she is expected to be highly motivated and willing to perform animal studies. Expertise in working with retroviral vectors would be a plus.

The position will be open in October 2011. The salary will be according to the German TV-L 13.
Interested applicants are invited to send a copy of their curriculum vitae, contact information for 3 references (address, phone number, email), and a brief statement of career goals to: Administration Department of the University Hospital of Münster, Albert-Schweitzer-Campus 1, Gebäude D5, 48149 48149 Münster, Germany and also via email to zarbock@uni-muenster.de. For further information please contact us on +49-251-70365-253.

In the case of similar qualification, competence, and specific achievements, women will be considered on preferential terms within the framework of the legal possibilities.
Handicapped candidates with equivalent qualifications will be given preference.