Tuesday, January 11, 2011

PostDoc in cell biology of cardiovascular disease in University of Heidelberg, Germany

A post-doctoral research position is available immediately for an exciting, interdisciplinary research project at Heidelberg University Medical Faculty and the European Molecular Biological Laboratories (EMBL).
The successful candidate will conduct a challenging research project that aims at the molecular characterization of genes pre-disposing for elevated blood cholesterol levels, a major risk factor for atherosclerosis and coronary heart disease. Specifically, the project seeks to investigate the cell biological and pathogenic function of selected candidate genes that have been identified in recent genome-wide association studies (GWAS) as associated with blood lipid traits. For this, the candidate will apply technologies developed in our laboratories that now make it possible to accomplish detailed cell-based loss-of-function studies of many genes in parallel using state-of-the-art microscopy.

The project is part of the prestigious transatlantic research alliance Molecular mechanisms of novel genes associated with plasma lipids and cardiovascular disease funded by the Fondation Leducq (http://www.fondationleducq.org/index.php). The position will be hosted within the stimulating international environment of the Molecular Medicine Partnership Unit (MMPU), a successful joint venture between the Medical Faculty of the University of Heidelberg and EMBL with the mission to strengthen the link between molecular research and medicine (http://www.klinikum.uni-heidelberg.de/MMPU).

We seek highly motivated candidates, ideally with qualifications in the areas of cell biology, functional genomics, bioinformatics and molecular medicine. The position is funded for an initial 2 years, but may be extendable for up to 5 years.

Contact:
Heiko Runz (heiko.runz@med.uni-heidelberg.de)
Institute of Human Genetics
Molecular Medicine Partnership Unit (MMPU)
INF 366, 69120 Heidelberg, Germany
http://www.klinikum.uni-heidelberg.de/Cholesterol-Regulation.114487.0.html
http://www.embl.de/research/partnerships/mmpu/research_groups/cholesterol_regulation/index.html
References:
Bartz, F. et al. Identification of cholesterol regulating genes by targeted RNAi-screening. Cell Metabolism (2009) 10:63-75.
Neumann, B. et al. Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature (2010) 464:721-727.